Core Product Advantages

1. Sensitive and Accurate Detection

Adopts high-precision gene sequencing technology to accurately detect disease-related and drug-related genes, with high detection sensitivity and accuracy, ensuring the reliability of test results and laying a solid foundation for clinical risk assessment and medication guidance.

1. Authoritative and Efficient Analysis

Based on authoritative genetic research evidence and standardized detection processes, the product completes the whole process from sample reception to report release with high efficiency, and provides professional and standardized test reports for clinical decision-making.

1. Convenient and Flexible Application

Supports standardized sample detection and streamlined experimental operation, with flexible and convenient detection process, which is suitable for large-scale clinical screening and personalized health assessment, and meets the diversified testing needs of medical institutions and individuals.

Key Detection Content

1. Hereditary Early-Onset Coronary Heart Disease Risk Genes

Accurately detects core risk-associated genes including LDLR, LDLRAP1, PCSK9, ABCG5, ABCG8 and APOB, which are closely related to the pathogenesis of hereditary early-onset coronary heart disease, realizing early screening and risk warning of the disease.

1. Statin-Related Medication Evaluation Genes

Specialized analysis of statin drug-related genes to comprehensively evaluate the adverse reaction risk and therapeutic effectiveness of statin drugs for individuals, providing a scientific genetic basis for clinical personalized medication selection and dosage adjustment.

Applicable Population

1. People with early-onset coronary heart disease and other cardiovascular diseases
2. People with a family history of early-onset coronary heart disease or imaging evidence of atherosclerosis
3. People with hypertension, hyperglycemia and hyperlipidemia (adult serum LDL-C ≥ 4.1 mmol/L)
4. People whose first-degree relatives have any one or all of the above three conditions
5. People with hypercholesterolemia and sitosterolemia
6. People concerned about cardiovascular health and willing to conduct proactive health screening

Clinical Significance

1. Genetic Risk Indication

Accurately identify the genetic susceptibility of individuals to hereditary early-onset coronary heart disease, and provide clear genetic risk prompts for high-risk groups to realize early intervention of the disease.

1. Statin Medication Guidance

Evaluate the individual response to statin drugs from the genetic level, guide clinicians to formulate personalized medication plans, improve the therapeutic effect of drugs and reduce the risk of adverse drug reactions.

1. Comprehensive Health Screening

Serve as an important means of cardiovascular health screening, and help asymptomatic people find potential genetic risks in time through active detection.

1. Professional Risk Assessment

Provide a scientific basis for the comprehensive cardiovascular risk assessment of the tested population, and help medical institutions formulate targeted health management and disease prevention plans.

Standard Detection Process

1. DNA extraction
2. Sample quality control
3. Library preparation
4. Library quality control
5. Gene sequencing (based on S100 Gene Sequencer)
6. Bioinformatics data analysis
7. Professional report review
8. Formal report release

Rapid Lead Time

The whole detection process is highly efficient, and the professional test report can be completed and released within 7 working days after receiving the qualified samples, ensuring the timeliness of clinical diagnosis and health management decision-making.