Principle >

The excitation light generated by the laser light source is reflected by the dichroic mirror and then coupled to a multimode optical fiber by the objective lens. The optical fiber transmits the excitation light to a specific brain area of ​​the experimental animal. The neurons in this brain area are specifically labeled with calcium-sensitive protein probes. These fluorescent probes express the neural activity signals in the form of fluorescent signals under the stimulation of the excitation light. The changing fluorescence signals are transmitted back to the detection optical path through the optical fiber, collected and converted by the photoelectric conversion device, and displayed and recorded.

Application >

 

Giving water and eating activates reward cells in the brain

Social behavior activates reward cells in the brain